Senior Linux Systems Engineer
Ultima Genomics — Tracked from its greenhouse job board
About the role
Rapidly Growing Life Sciences Technology Company
Ultima Genomics is a rapidly growing company that is developing ground-breaking genomics technologies. Our mission is to continuously drive the scale of genomic information to enable unprecedented advances in biology and improvements in human health. We have developed a foundational new approach to sequencing at scale that overcomes limitations due to the high costs of current technologies. We are well-funded and have raised approximately $600 million from global top-tier investors. Our team brings together unique and diverse expertise across multiple disciplines, from healthcare and life sciences, to engineering, to technology and software and beyond. We are a collaborative group, including successful entrepreneurs, chemists, hardware and software engineers, genomics and biotechnology experts, molecular and computational biologists, software and algorithm experts, and operations and commercial leaders. Join us to develop and commercialize technologies that unleash the power of genomics at scale and empower the future of human health.
We are looking for a highly motivated Senior Linux Systems Engineer to join our Computing Team!
You will work on high-performance computing (HPC) systems that are part of our sequencing platform. The ideal candidate is a hands-on Linux expert who thrives on optimizing performance and building secure, scalable and reliable systems in a fast-paced environment.
This is a full-time, on-site position at our Fremont, CA headquarters.
How You’ll Contribute
Design, build, and maintain high-performance Linux systems supporting compute and data-intensive workloads
Optimize system performance through kernel and filesystem tuning; identify and eliminate I/O, memory, or network bottlenecks
Automate provisioning and configuration management using orchestration tools such as Ansible and Salt
Monitor and troubleshoot kernel, driver, and hardware issues; perform root cause analysis in partnership with data and engineering teams and propose long-term solutions
Ensure system reliability through regular patching, monitoring, and performance tuning
Maintain accurate system documentation, runbooks, and configuration baselines
Collaborate with software, hardware, and scientific teams to ensure platform reliability and scalability
Other duties as assigned
Qualifications, Skills, Knowledge & Abilities
BS in Computer Science, Engineering, or related field
5+ years of experience designing and building high-performance physical Linux systems in high-throughput or mission-critical environments
Deep knowledge of Linux kernel, NFS and Linux file system performance tuning
Solid background in TCP/IP networking, routing, VLANs, and firewall rules
Experience with the latest CPU and GPU technologies
Proficiency in shell scripting (bash), working knowledge of Python, and familiarity with Ansible or similar configuration management tools
Proven hands-on experience building servers from components, diagnosing hardware failures, and working with vendors
Excellent documentation and communication skills
May occasionally be exposed to activity that requires pulling/lifting/moving/carrying up to 50 lbs
Experience with cloud computing infrastructure (e.g. AWS) and Docker desirable
Familiarity with security frameworks and compliance standards (e.g. ISO 27001) a plus
At Ultima Genomics, your base pay is one part of your total compensation package. This role pays between $125,000 and $150,000, if performed in California, and your actual base pay will depend on your skills, qualifications, experience, and location. Please note that the compensation details listed in US role postings reflect the base salary only, and do not include bonus, equity, or benefits. This role is also eligible for a competitive benefits package that includes: medical, dental, vision, life, and disability insurance; 401(k) retirement plan; flexible spending & health savings account; paid holidays; paid time off; employee assistance program; and other company benefits. #LI-Onsite
Ultima Genomics is proud to be an equal opportunity workplace and is an affirmative action employer. We provide equal employment opportunity for all applicants and employees. We do not discriminate on the basis of race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), gender identity, gender expression, national origin, ancestry, citizenship, age, physical or mental disability, military or veteran status, marital status, domestic partner status, sexual orientation, genetic information, or any other basis protected by applicable laws. See also Ultima Genomics’ EEO Policy and Know Your Rights . If you have a disability or special need that requires accommodation, please let us know by contacting recruiting@ultimagen.com .
What the index says about this role
- First seen by JobLarper — Aug 2, 2026, 6 days ago. Older postings collect hundreds of applicants — a tailored résumé matters more the longer a role has been live.
- No pay range in our index for this listing. Across 177 indexed DevOps & Site Reliability Engineer roles in US that do publish one, the middle half sits between $165k and $250k, median $204k — JobLarper's read of the market, not a figure from Ultima Genomics.
- What DevOps & Site Reliability Engineer roles ask for — across 1,405 indexed openings: Cloud (50%), Python (41%), REST/APIs (33%), Go (31%), Backend (24%). This posting names Cloud, Python, React Native.
- Ultima Genomics is hiring actively — 7 open roles indexed.
Derived from the 26,996 roles JobLarper indexes daily from official company boards — not from the job description above.
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All 7 open roles at Ultima Genomics →
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