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Sr. Software Engineer - ML Systems

Cleerly — AI · AI Technology · Apps

Denver, Colorado, United States Senior+ Posted Apr 13, 2026
PythonSQLREST/APIsCloudML

About the role

About Cleerly

We’re Cleerly – a healthcare company that’s revolutionizing how heart disease is diagnosed, treated, and tracked. We were founded in 2017 by one of the world’s leading cardiologists and are a growing team of world-class engineering, operations, medical affairs, marketing, and sales leaders. We raised $223M in Series C funding in 2022 which has enabled rapid growth and continued support of our mission. In December 2024 we received an additional $106M in a Series C extension funding. Most of our teams work remotely and have access to our offices in Denver, Colorado, New, York, New York, Dallas, Texas, and Lisbon, Portugal with some roles requiring you to be on-site in a location.

Cleerly has created a new standard of care for heart disease through value-based, AI-driven precision diagnostic solutions with the goal of helping prevent heart attacks. Our technology goes beyond traditional measures of heart disease by enabling comprehensive quantification and characterization of atherosclerosis, or plaque buildup, in each of the heart arteries. Cleerly’s solutions are supported by more than a decade of performing some of the world’s largest clinical trials to identify important findings beyond symptoms that increase a person’s risk of heart attacks.

At Cleerly, we collaborate digitally and use a wide variety of systems. Our people use Google Workspace (GMail, Drive, Docs, Sheets, Slides), Slack, Confluence/Jira, and Zoom Video, prior experience in these areas is a plus. Role or department specific technology needs may vary and will be listed as requirements in the job description.

While we are mostly a remote company, travel is required for some team meetings and cross function projects typically once per month or once per quarter, for some roles like sales or external facing roles travel could be up to 90% of the time.

Cleerly is committed to providing safe and effective medical software that meets customer needs and our intended use. The adherence to all applicable regulatory and statutory requirements establishes a clear framework for setting measurable quality objectives. Our commitment to continually improving our products and processes proactively manages risks, ensuring ongoing compliance throughout the entire software lifecycle. Understanding this role's relevance and importance is critical to achieving Cleerly's quality objectives.

About the Opportunity

We are seeking a Senior Software Engineer to design, build, deploy, monitor, and optimize production-ready ML services in regulated healthcare. You will work hands-on to package, test, orchestrate, deploy, and maintain ML models, improve workflows, and implement CI/CD and automated testing to ensure reliability, performance, and faster delivery of business value.

Responsibilities

Design, build, and deploy scalable AI/ML services with clear service boundaries, making pragmatic trade-offs across performance, maintainability, security, and long-term extensibility.

Own full lifecycle delivery of complex features from architectural planning and API design to implementation and post-release observability.

Define and enforce robust verification and validation for AI services including unit, integration, and end-to-end testing to ensure reliability of code in production and compliance with our Quality Management System and regulatory standards.

Integrate CI/CD and MLOps practices for automated model builds, testing, and deployment.

Translate product requirements into well-defined technical designs proactively shaping implementation details.

Contribute to the necessary technical documentation required for regulatory submissions.

Collaborate cross functionally to reduce knowledge silos and ensure continuity in critical systems through cross-training and documentation.

Requirements

Bachelor’s or Master’s degree in Computer Science, Software Engineering, or related field

7+ years of software engineering experience, with expertise in AI production systems (Python, PyTorch) and data services (SQL, Postgres, NoSQL, Redis or similar).

Experience with unit, integration testing for ML models, including data validation, correctness checks, and reproducibility.

Experience with CI/CD, Orchestration tools (Airflow, MLflow, Kubernetes, Terraform) and ML/data platforms(SageMaker, Databricks, Unity Catalog, Snowflake/Snowpark) to build scalable ML data pipelines and model workflows.

Strong collaboration skills to work effectively with ML scientists, engineers, and regulatory teams.

Comfortable operating in ambiguity and driving clarity across product, engineering, and business stakeholders.

This role is eligible for a 15% target annual bonus , resulting in the following base salary and Total Target Compensation (TTC) ranges:

Base Salary: $153,000 - $179,000

TTC: $176,000 - $206,000

*Total Target Compensation (TTC): Total Cash Compensation (including base pay, variable pay, commission, bonuses, etc.) Additionally, stock options, paid benefits, and employee perks are part of your total rewards.

Working at Cleerly takes HEART. Discover our Core Values:

H: Humility - be a servant leader

E: Excellence - deliver world-changing results

A: Accountability - do what you say; expect the same from others

R: Remarkable - inspire & innovate with impact

T: Teamwork - together we win

Don’t meet 100 percent of the qualifications? Apply anyway and help us diversify our candidate pool and workforce. We value experience, whether gained formally or informally on the job or through other experiences. Job duties, activities and responsibilities are subject to change by our company.

OUR COMPANY IS AN EQUAL OPPORTUNITY EMPLOYER. We do not discriminate on the basis of race, color, national origin, ancestry, citizenship status, protected veteran status, religion, physical or mental disability, marital status, sex, sexual orientation, gender identity or expression, age, or any other basis protected by law, ordinance, or regulation.

For more information see our Privacy Policy ( https://cleerlyhealth.com/privacy-policy) . All official emails will come from @cleerlyhealth.com email accounts.

#Cleerly

What the index says about this role

  • First seen by JobLarper — Aug 2, 2026, 6 days ago. Older postings collect hundreds of applicants — a tailored résumé matters more the longer a role has been live.
  • No pay range in our index for this listing. Across 1,685 indexed Software Engineer roles in US that do publish one, the middle half sits between $185k and $285k, median $225k — JobLarper's read of the market, not a figure from Cleerly.
  • What Software Engineer roles ask for — across 10,230 indexed openings: REST/APIs (46%), Backend (42%), Cloud (38%), Python (38%), Go (25%). This posting names REST/APIs, Cloud, Python, ML.
  • Cleerly is hiring actively — 9 open roles indexed.

Derived from the 27,000 roles JobLarper indexes daily from official company boards — not from the job description above.

⚡ JobLarper watched this role appear on Cleerly's official board on Apr 13, 2026. Sign up free to get alerted minutes after roles like this go live, and tailor your real résumé to the exact description — nothing invented.

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