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Machine Learning Engineer - Computational Drug Discovery

4:59 — Tracked from its lever job board

Watertown, MA Mid Posted Jul 6, 2026
ML
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About the role

Our team is dedicated to the development of a broad pipeline of small molecules powered by unique chemistry insights to address a wide range of highly unmet clinical needs.  Our company was created within 5AM Ventures' 4:59 Initiative in 2023.

The computational team has roots from D. E. Shaw Research, one of the most rigorous computational science environments in the world. You will work directly with and learn from scientists who have operated at the frontier of computational drug discovery.

What the index says about this role

  • First seen by JobLarper — Aug 2, 2026, 6 days ago. Older postings collect hundreds of applicants — a tailored résumé matters more the longer a role has been live.
  • No pay range in our index for this listing. Across 193 indexed Machine Learning Engineer roles in US that do publish one, the middle half sits between $213k and $300k, median $250k — JobLarper's read of the market, not a figure from 4:59.
  • What Machine Learning Engineer roles ask for — across 1,108 indexed openings: ML (78%), AI/LLM (55%), Python (53%), REST/APIs (38%), Cloud (25%). This posting names ML.

Derived from the 27,000 roles JobLarper indexes daily from official company boards — not from the job description above.

⚡ JobLarper watched this role appear on 4:59's official board on Jul 6, 2026. Sign up free to get alerted minutes after roles like this go live, and tailor your real résumé to the exact description — nothing invented.

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